Small molecule modulators exhibit an exceptional capacity to regulate the innate immune response, presenting promising prospects for therapeutic interventions across a diverse array of diseases.

Utilizing high-throughput screening (FDA approved drug libraries), Omics and leveraging AI-based models, our objective is to elucidate the intricate interactions between these small molecules and innate immune signaling pathways. We aim to discern the mechanisms by which these compounds engage with and impact the activation, regulation, and nuanced adjustments within the innate immune system's responses. This multifaceted approach holds the key to unlocking valuable insights into how small molecule modulators influence innate immunity, paving the way for innovative strategies in therapeutic development.