In our world, diverse pathogens, including bacteria, viruses, fungi, and parasites, perpetually challenge our well-being. Despite this perpetual assault, our bodies adeptly maintain equilibrium and health, largely thanks to the vigilance of our innate immune system.
Within our bodies, specialized cells such as macrophages, neutrophils, and dendritic cells play pivotal roles in detecting and combating these invaders. These cells possess an array of receptors—both membrane-bound and cytosolic—that act as sentinels, recognizing and responding to invading pathogens. Upon activation, these receptors initiate the release of cytokines, crucial molecules that orchestrate the immune response, ultimately eliminating the intruders.
However, the immune system's response is not universal; it varies based on the type of pathogen or its variant, demanding distinct immune reactions mediated by different receptors. This realization propels our research mission: to unearth novel receptors responsible for sensing these pathogens. Employing cutting-edge techniques, we endeavor to uncover and characterize these elusive receptors, shedding light on the intricate mechanisms underlying pathogen recognition.
Join us on our quest to unravel the mysteries of immune-pathogen interactions and pave the way for innovative approaches in understanding and combating infectious diseases.