"ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)"

Balaji Banoth, Shraddha Tuladhar, Rajendra Karki, Bhesh Raj Sharma, Benoit Briard, Sannula Kesavardhana, Amanda Burton, Thirumala-Devi Kanneganti, Journal of Biological Chemistry, Dec 25, 295(52), 18276-18283

"Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense"

Min Zheng, Rajendra Karki, Peter Vogel, Thirumala-Devi Kanneganti, Cell, 2020 Apr, 181(3), 674-687

"DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome"

Parimal Samir #, Sannula Kesavardhana #, Deanna M Patmore #, Sebastien Gingras, R K Subbarao Malireddi, Rajendra Karki, Clifford S Guy, Benoit Briard, David E Place, Anannya Bhattacharya, Bhesh Raj Sharma, Amanda Nourse, Sharon V King, Aaron Pitre, Amanda, Nature, 2019 Sep, 573(7775), 590-594

"Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging"

Hanzhi Luo, Wei-Chieh Mu, Rajendra Karki, Hou-Hsien Chiang, Mary Mohrin, Jiyung J Shin, Rika Ohkubo, Keisuke Ito, Thirumala-Devi Kanneganti, Danica Chen, Cell Reports, 2019 Jan, 26(4), 945-954

"Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice"

Bhesh Raj Sharma, Rajendra Karki, Ein Lee, Qifan Zhu, Prajwal Gurung, Thirumala-Devi Kanneganti, Cell Death and Differentiation, 2019 Mar, 26(4), 741-750

"Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection"

Benoit Briard, Rajendra Karki, R K Subbarao Malireddi, Anannya Bhattacharya, David E Place, Jayadev Mavuluri, Jennifer L Peters, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Nature Microbiology, 2019 Feb, 4(2), 316-327

"Role of AIM2 inflammasome in inflammatory diseases, cancer and infection"

Bhesh Raj Sharma, Rajendra Karki, Thirumala-Devi Kanneganti, European Journal of Immunology, 2019 Nov, 49(11), 1998-2011

"Diverging inflammasome signals in tumorigenesis and potential targeting"

Rajendra Karki, Thirumala-Devi Kanneganti, Nature Reviews Cancer, 2019 Apr, 19(4), 197-214

"ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming"

David E Place, Parimal Samir, Rajendra Karki, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti, American Journal of Pathology, 2018 Apr, 188(4), 1021-1030

"Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis"

Deepika Sharma, Ankit Malik, Clifford S Guy, Rajendra Karki 1, Peter Vogel 2, Thirumala-Devi Kanneganti 3, Gastroenterology, 2018 Mar, 154(4), 948-964

"Phytochemical profile and pharmacological activity of Aegle marmelos Linn."

Bikash Manandhar, Keshav Raj Paudel, Biraj Sharma, Rajendra Karki*, Journal of Integrative Medicine, 2018 May, 16(3), 153-163

"Gasdermin D promotes AIM2 inflammasome activation and is required for host protection against francisella novicida"

Qifan Zhu, Min Zheng, Arjun Balakrishnan Rajendra Karki, Thirumala-Devi Kanneganti, Journal of Immunology, 2018 Dec, 201(12), 3662-3668

"IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation"

Rajendra Karki#, Ein Lee#, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R K Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti, Cell, 2018 May, 173(4), 920-933

"Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa"

Arjun Balakrishnan, Rajendra Karki, Brent Berwin, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Cell Death Discovery, 2018 Jun, 4:3,

"Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection"

Qifan Zhu, Si Ming Man, Rajendra Karki, R K Subbarao Malireddi, Thirumala-Devi Kanneganti, Cell Reports, 2018 Mar, 22(12), 3168-3174