"Innate immunity, cytokine storm, and inflammatory cell death in COVID-19"

Karki R.; Kanneganti T.-D., Journal of translational medicine, 2022, 20(1), 542

"Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation"

Wang Y.; Karki R.; Mall R.; Sharma B.R.; Kalathur R.C.; Lee S.; Kancharana B.; So M.; Combs K.L.; Kanneganti T.-D., Cell reports, 2012 Oct, 4;41(1), 111434

"Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method"

Wang Y.; Pandian N.; Han J.-H.; Sundaram B.; Lee S.J.; Karki R.; Guy C.S.; Kanneganti T.-D., Cellular and Molecular Life Sciences, 2022 Sep 28, 79(10), 531

"ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection"

Karki R.#; Lee S.#; Mall R.; Pandian N.; Wang Y.; Sharma B.R.; Malireddi R.K.S.; Yang D.; Trifkovic S.; Steele J.A.; Connelly J.P.; Vishwanath G.; Sasikala M.; Reddy D.N.; Vogel P.; Pruett-Miller S.M.; Webby R.; Jonsson C.B.; Kanneganti T.-D., Science Immunology, 2022 Aug, 26;7(74), eabo6294

"NLRC4 Deficiency Leads to Enhanced Phosphorylation of MLKL and Necroptosis"

Sundaram B.; Karki R.; Kanneganti T.-D., Immuno Horizons, 2022 Mar, 17;6(3), 243-252

"The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis"

Sharma B.R.†; Karki R.†; Sundaram B.; Wang Y.; Vogel P.; Kanneganti T.-D.*, Cancers, 2022 Feb, 14(4), 919

"Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth"

R K Subbarao Malireddi#, Rajendra Karki#, Balamurugan Sundaram#, Balabhaskararao Kancharana#, SangJoon Lee, Parimal Samir, Thirumala-Devi Kanneganti, ImmunoHorizons, 2021 Jul, 21;5(7), 568-580

"AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence"

SangJoon Lee, Rajendra Karki, Yaqiu Wang, Lam Nhat Nguyen, Ravi C Kalathur, Thirumala-Devi Kanneganti, Nature, 2021 Sep, 597(7876), 415-419

"ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis"

Rajendra Karki, Balamurugan Sundaram, Bhesh Raj Sharma, SangJoon Lee, R K Subbarao Malireddi, Lam Nhat Nguyen, Shelbi Christgen, Min Zheng, Yaqiu Wang, Parimal Samir, Geoffrey Neale, Peter Vogel, Thirumala-Devi Kannegani, Cell reports, 2021 Oct, 37(3), 109858

"Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection"

Yaqiu Wang, Rajendra Karki, Min Zheng, Balabhaskararao Kancharana, SangJoon Lee, Sannula Kesavardhana, Baranda S Hansen, Shondra M Pruett-Miller, Thirumala-Devi Kanneganti, The Journal of immunology, 2021 Nov, 207(10), 2411-2416

"Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation"

Sarang Tartey, Prajwal Gurung, Rajendra Karki, Amanda Burton, Paul Hertzog, Thirumala-Devi Kanneganti, Cellular and molecular immunology, 2021 Jul, 18(7), 1798-1808

"DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response"

Sannula Kesavardhana, Parimal Samir, Min Zheng, R K Subbarao Malireddi, Rajendra Karki, Bhesh Raj Sharma, David E Place, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti, The Journal of biological chemistry, 2021 Jan-Jun, 296:100579,

"TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines"

Min Zheng, Rajendra Karki, Evan Peter Williams, Dong Yang, Elizabeth Fitzpatrick, Peter Vogel, Colleen Beth Jonsson, Thirumala-Devi Kanneganti, Nature immunology, 2021 Jul, 22(7):829-838,

"The 'cytokine storm': molecular mechanisms and therapeutic prospects"

Rajendra Karki , Thirumala-Devi Kanneganti, 2021 Aug, 42(8), 681-705

"Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections"

Min Zheng, Rajendra Karki, Balabhaskararao Kancharana, Hartmut Berns, Shondra M Pruett-Miller, Thirumala-Devi Kanneganti, The Journal of biological chemistry, 2021 Dec, 297(6):, 101379